Public Health and Primary CareCASE REPORT

Perplexing Rash: Challenges to Diagnosis and Management of Mycosis Fungoides

Jonathan A. Aun, DO; Hamish S. Patel, DO; Kinal K. Patel, DO; Jeffrey Cashman, DO; and Elizabeth Bailey, MD
Notes and Affiliations
Notes and Affiliations

Received: December 30, 2017

Accepted: January 30, 2018

Published: July 1, 2018

J Osteopath Med; 118(7): 472-478

Mycosis fungoides is the most ubiquitous form of cutaneous T-cell lymphoma. Diagnosis is arduous, as early phases often resemble common inflammatory dermatoses. The principal histologic features of MF include medium to large-sized cerebriform mononuclear cells in single or small clusters in the epidermis. Treatment modalities are prodigious and relapses are common. The authors present a case of a 69-year-old man with mycosis fungoides, followed by a review of diagnostic modalities and phototherapeutic interventions for patients with this condition. According to literature reports, monochromatic excimer light therapy is the most advantageous and well-tolerated phototherapy modality for patients with early patch stage mycosis fungoides.

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