Cardiopulmonary MedicineREVIEW

Cardiovascular Disease as a Result of the Interactions Between Obesity, Climate Change, and Inflammation: The COCCI Syndemic

Michael Clearfield, DO; Glenn Davis, MS; Jennifer Weis, DO; Gregory Gayer, PhD; and Jay H. Shubrook, DO
Notes and Affiliations
Notes and Affiliations

Accepted: January 17, 2018

Published: November 1, 2018

J Osteopath Med; 118(11): 719-729

Obesity and climate change conspire to create an environment in which subclinical vascular inflammation leads to progressive atherosclerosis, which contributes to the number 1 cause of global mortality: cardiovascular disease. The syndemic model requires 2 or more diseases or contributors to disease (such as obesity and climate change) clustering within a specific population in addition to the associated societal and social factors, ultimately creating an environment supportive of a greater adverse interaction. This article explores the syndemic of obesity and climate change as a driver for cardiovascular disease.

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