Advance Articles

NMM/OMT

Osteopathic manipulative treatment of patients with chronic low back pain in the United States: a retrospective cohort study

John C. Licciardone, DO, MS, MBA, FACPM; Samuel Moore, BS; Kassidy Fix, BS; Lillian Gowen Blair, MS; and Khanh Ta, BS
This study analyzes the factors associated with OMT use and its outcomes when integrated within the overall medical care for chronic low back pain provided by osteopathic physicians in the United States.
Advance Article
Letters to the Editor

Osteopathic manipulative techniques in the treatment of vestibular dizziness not related to the cervical spine

Gerard Alvarez, PhD, MSc, PT, DO; Sergi Lucas, MSc, PT, DO; and Sònia Roura, MSc, PT, DO
Advance Article
Medical Education

Barriers to research opportunities among osteopathic medical students

Angela Ho, BS; Alyssa Auerbach, DO; Jantzen J. Faulkner, BS; Satvinder K. Guru, BA; Amber Lee, MS; and David Manna, PhD
The authors assess the barriers that osteopathic medical students face when seeking research opportunities, identify resources currently available to osteopathic medical students at their respective schools, and investigate factors that contribute to an osteopathic medical student’s desire to pursue research opportunities.
Advance Article
Clinical Image

Superficial spreading melanoma within a nevus spilus

Jennifer Racanelli, DO; Mairead Moloney, BS; and Louis Siegel, DO, FAAD
Advance Article
NMM/OMT

Does the osteopathic pedal pump reduce lower limb volume in healthy subjects?

Jill S. Adams, BS; Sahil H. Parikh, BS; Brandon J. Goodwin, BA; and Donald R. Noll, DO, FACOI
Lymphatic treatments are gentle and passive techniques believed to enhance movement of lymph back into the central circulatory system. Animal studies provide supportive evidence, yet there are few studies in humans. The study investigates whether the osteopathic pedal pump protocol reduces volume in the lower limbs of healthy subjects.
Advance Article
General

Glucocorticoid use in rheumatoid arthritis patients and the onset of pneumonia: a systematic review and meta-analysis

Kawther N. Elsouri, BS, MS; Vania Arboleda, BS; Lynn Basbous, BS; Samantha Heiser, BS, MS; Dylon P. Collins, BS; Philip Ragusa, BS; Courney Baxter, BS; Dominick Cabrera, BS, MS; Tanisha Akhand, BS; Evan Stermer, BS, MS; Kiran Sharma, BS; Charmaine Seguro, BS, MS; Patrick Hardigan, PhD; Marc Kesselman, DO; and Michelle Demory Beckler, PhD
The goal of this study was to systematically review and statistically analyze pooled data documenting pneumonia as an adverse event in rheumatoid arthritis (RA) patients on disease-modifying antirheumatic drugs (DMARDs) as a monotherapy vs RA patients on DMARDs and glucocorticoids as combination therapy.
Advance Article
Musculoskeletal Medicine and Pain

Structural abnormalities and osteopathic considerations in primary immunodeficiencies

Marija J. Rowane, DO; Meghan A. Callahan, BS; Jason E. Schend, DO; Michael P. Rowane, DO, MS, FAAFP, FAAO; and Robert W. Hostoffer, DO, LhD, MSMEd, FACOP, FAAP, FCCP, FACOI
In this case report, the authors describe the first concise osteopathic examination of an immunodeficient patient with a phosphatidylinositol 3-kinase regulatory subunit 1 (PIK3R1) mutation and provide a review of musculoskeletal abnormalities found in more common primary immunodeficiencies.
Advance Article
NMM/OMT

Enabling health potential: exploring nonlinear and complex results of osteopathic manual medicine through complex systems theory

Leslie M. Ching, DO; Bruce A. Benjamin, PhD; Edward G. Stiles, DO; and Harriet H. Shaw, DO
In this paper, complex systems theory is explored as a paradigm to understand how the body works, how it breaks down biomechanically and physiologically, how disease states can be viewed from a systems perspective, and how osteopathic manipulative medicine may interact with the complex adaptive system of the body to change entrenched neurologic patterns and improve patients’ potential for health.
Advance Article
Pediatrics

Evaluation of academic detailing to educate clinicians regarding childhood lead poisoning prevention: a pilot study

Nicholas C. Newman, DO, MS; Jacqueline M. Knapke, PhD; Rachael Kiniyalocts, BA; John Belt, MS; and Erin Haynes, DrPH
The objectives of this study were to implement a pilot of academic detailing sessions on the topic of childhood lead poisoning prevention with frontline healthcare providers and their staff in different practice settings, and to evaluate the acceptability of these training sessions utilizing quantitative and qualitative methods.
Advance Article
NMM/OMT

Connecting the dots: alterations in bioelectric activity at acupuncture Ting (Jing-Well) points following CV4 cranial manipulation

Jan T. Hendryx, MS, DO; Ashok Kannan, DO; Jessica Prashad, MMS; and Karl Falk, DO
By measuring specific electrical parameters at acupuncture points that have been shown to correlate with autonomic nervous system (ANS) activity, the objectives of this study were to: (1) determine if compression of the fourth ventricle (CV4) has any influence on the bioelectric properties of the acupuncture meridian system; and (2) determine if CV4 affects the ANS.
Advance Article
General

The presence of person-centered language in orthopedic-related amputation research: a cross-sectional analysis

Arjun K. Reddy, BA; Grayson R. Norris, BS; Rob Nayfa, BS; Nicholas B. Sajjadi, BS; Jake X. Checketts, DO; Jared T. Scott, DO; and Micah Hartwell, PhD
Amputations are routine in orthopedics, specifically during trauma and when patients have recurrent surgical site infections. When undergoing amputations, patients must combat the psychosocial factors associated with the loss of an extremity, including stigmatization. This study analyzes the presence of person-centered language within amputation-related orthopedic publications in the top orthopedic journals.
Advance Article
Musculoskeletal Medicine and Pain

Revisiting chronic low back pain: evidence that it is not non-specific

Clarence L. Nicodemus, DO, PhD; Alla Sikorskii, PhD; and Jessica Epstein, MS
The objective of this study is to show that chronic low back pain (CLBP) presents as a pattern of symptoms that actually represents the final common pathway for a dysfunctional lumbosacropelvic joint system. Rather than being “nonspecific,” the majority of CLBP has an underlying cause that is quite specific and predictable.
Advance Article
General

Understanding and preference toward DOs and OMT before and after an osteopathic principles and practice fellow lecture series

Lindsay Ellson, MS; Nicole Wong, MS; Jessica Harper, BS; Gage Williamson, DO; Isain Zapata, PhD; Kristin Putnam, DO; and Joel Roberts, MD
The main objective of our study was to investigate the preferences of Master of Science in Biomedical Sciences (MSBS) students at an osteopathic institution regarding osteopathic medicine and to investigate whether an active intervention can change their preferences and understanding.
Advance Article
Behavioral Health

Adverse childhood experience categories and subjective cognitive decline in adulthood: an analysis of the Behavioral Risk Factor Surveillance System

Rachel M. Terry, BS; Sadie E. Schiffmacher, BS; Avery A. Dutcher, BS; Julie M. Croff, PhD; Martina J. Jelley, MD; and Micah L. Hartwell, PhD
Adverse childhood experiences (ACEs) negatively impact health outcomes later in life, in a dose–dependent relationship; however, little is known about the impact of the individual ACE categories and subjective cognitive decline later in life. The aim of this study was to determine the associations among eight ACEs and subjective cognitive decline.
Advance Article
Clinical Image

Annular bullous lesions in a child from Uganda: chronic bullous disease of childhood

Austin B. Ambur, DO; Timothy A. Nyckowski, DO; and Aashni Bhukhan, BS
Advance Article
Public Health and Primary Care

Effects of face masks on oxygen saturation at graded exercise intensities

Varnita Vishwanath, BSc; Clinnt L. Favo, MA; Trevyn H. Tu, MA; Blake Anderson, BS; Colby Erickson, MA; Megan Scarpulla, MA; Julia Kern, MA; Lisa DeWinter, MD; Anette Gawelko, DO; Charlotte Bolch, PhD; and Layla Al-Nakkash, PhD
Mask wearing to mitigate the spread of COVID-19 and other viral infections may raise concerns on the effects of face masks on breathing and cardiopulmonary health. In this study, the authors assess the parameters related to heart and lung physiology between healthy male and female adults exposed to wearing face masks (or not) under conditions of rest and graded exercise.
Advance Article