Advance Articles

NMM/OMT

Lymphatic osteopathic manipulative treatment reduces duration of deltoid soreness after Pfizer/BioNTech COVID-19 vaccine

Sylvia Marshall, OMS III; Sara Winter, PA-C, MS; and John D. Capobianco, DO, FAAO
Pfizer-BioNTech BNT162b2 is one of the three U.S. Food and Drug Administration (FDA)-approved vaccines for the prevention of COVID-19. Its most common side effect, injection site pain, occurs because of locally recruited inflammatory mediators and is mitigated by the lymphatic system. Side effects may discourage individuals from receiving vaccines; therefore, reducing the duration of injection site pain can promote vaccination compliance. Osteopathic manipulative treatments (OMT) can directly affect the physiology underlying muscle soreness; however, there is currently no literature that supports the use of OMT in this scenario. In this case report, an otherwise healthy male presented with acute left deltoid soreness after receiving the Pfizer COVID-19 vaccine. Three hours after being treated with lymphatic OMT, the severity of the pain was significantly reduced and was alleviated 8 hours after onset in comparison to the median duration of 24–48 hours.
Advance Article
Public Health and Primary Care

A novel movement system screen for primary care providers: a multisite, observational study

Christine Kettle, DPT; Lauren McKay, DO; Anthony M. Cianciolo, DO; Stephen M. Kareha, DPT, ATC, PhD; and Cara E. Ruggeri, DO
The authors evaluated whether a screening tool would be able to accurately screen individuals for movement system disorders (MSDs), explore comorbidities that may predict the prevalence of MSDs, and identify why people do not discuss these problems with their primary care provider.
Advance Article
NMM/OMT

Cranial manipulation affects cholinergic pathway gene expression in aged rats

Ramu Anandakrishnan, PhD; Hope Tobey, DO; Steven Nguyen, BS; Osscar Sandoval, BS; Bradley G. Klein, PhD; and Blaise M. Costa, PhD
Age-dependent dementia is a devastating disorder afflicting a growing older population. Although pharmacological agents improve symptoms of dementia, age-related comorbidities combined with adverse effects often outweigh their clinical benefits. Therefore, nonpharmacological therapies are being investigated as an alternative. In a previous pilot study, aged rats demonstrated improved spatial memory after osteopathic cranial manipulative medicine (OCMM) treatment. In this continuation of the aforementioned study, the authors examine the effect of OCMM on gene expression to elicit possible explanations for the improvement in spatial memory.
Advance Article
Pediatrics

Pediatric unilateral knee swelling: a case report of a complicated differential diagnosis and often overlooked cause

Katherine E. Guardado, OMS II; and Shane Sergent, DO
Lyme disease is the most common vector-borne illness in the United States. However, Lyme arthritis is a diagnosis that is often missed, even in children, who are the population with the highest incidence of Lyme disease. The authors present a case of a 3-year-old female presenting to the emergency department with a history of limping for 2 weeks. The mother of the child recognized a tick bite. However, the child was not taken to seek care expeditiously, because she had not developed any rashes. Test results demonstrated that the patient was IgG positive and IgM negative for Lyme disease, with Western blot confirming the diagnosis of Lyme arthritis.
Advance Article
Medical Education

The effectiveness of the metabolic map in promoting meaningful learning

Zeynep Gromley, PhD; Chinelo Agwuncha, OMS, I; Vinayak K. Nahar, MD, PhD; and Adam Gromley, PhD
Many medical students and practicing physicians view biochemistry, especially its metabolic pathways, as a challenging topic given the depth of material. Medical biochemistry educators aim to help prepare future physicians to apply knowledge of metabolism to disease processes. Research confirms that study tools promote critical thinking and help to connect biochemistry concepts to health and disease processes. This article explores whether the Pathways of Human Metabolism Map as a study tool helps to connect basic metabolic pathways to clinical applications.
Advance Article
Public Health and Primary Care

Glycemic control is associated with lower odds of mortality and successful extubation in severe COVID-19

Jay M. Pescatore, DO; Juan Sarmiento, MD; Ruben A. Hernandez-Acosta, MD; Britt Skaathun, PhD, MPH; Nancy Quesada-Rodriguez, MD; and Katayoun Rezai, MD
Corticosteroids, specifically dexamethasone, have become the mainstay of treatment for moderate to severe COVID-19. This study aims to analyze the association between corticosteroids and COVID-19–related outcomes in patients admitted to the medical ICU for COVID-19 pneumonia.
Advance Article
Medical Education

AOA ophthalmology and otolaryngology program closures as a model to highlight challenges of maintaining GME in high need areas

Harris Ahmed, DO, MPH; Kim Vo, MS; and Wayne Robbins, DO
The authors sought to determine the challenges faced by former AOA-accredited surgical subspecialty programs during the transition to ACGME accreditation, particularly otolaryngology and ophthalmology programs in underresourced settings.
Advance Article
General

A comparative study of the effectiveness of an osteopathic primary care sports medicine led intervention on performance in men’s collegiate lacrosse players

Naresh C. Rao, DO, FAOASM; Hallie Zwibel, DO; Jenny Berezanskaya, DO; Paul Pena, DO; and Min-Kyung Jung, PhD
In this study, the authors attempt to determine whether a comprehensive osteopathic primary care sports medicine approach can improve performance and health outcomes in collegiate athletes.
Advance Article
NMM/OMT

Effect of osteopathic manipulation on gait asymmetry

Cherice N. Hill, PhD; M’Lindsey Romero, DO; Mark Rogers, DO; Robin M. Queen, PhD; and Per Gunnar Brolinson, DO
Osteopathic manipulation treatments (OMTs) targeting identified somatic dysfunctions can correct structural asymmetries and malalignment, restoring the ability for proper compensation of stresses throughout the body. Little is currently known about the ability for OMTs to reduce gait asymmetries, thereby reducing the risk of injury, accelerated disease progression, and suboptimal recovery. The purpose of this study is to demonstrate whether osteopathic screening and treatment could alter movement and loading asymmetry during treadmill walking.
Advance Article
Clinical Image

Tracheobronchial cast

Emilie Offerman, DO; Samantha Mahon, MD; and Bradley Michael Golden, DO
Advance Article
Clinical Image

Demodex folliculitis: a masquerading entity

Armaan Guraya, BS, OMS IV; Robert Dazé, DO; and Krina Chavda, DO
Advance Article