Articles related toCardiopulmonary Medicine

Novel Dual-Fluorescent Mitophagy Reporter Reveals a Reduced Mitophagy Flux in Type 1 Diabetic Mouse Heart

Satoru Kobayashi, PhD; Joy Patel, BS; Fengyi Zhao, MD; Yuan Huang, MD; Tamayo Kobayashi, MS; and Qiangrong Liang, MD, PhD
Mitophagy is essential for maintaining healthy mitochondria for normal cardiac function. Patients with diabetes are at higher risk for heart damage. Researchers explored this complex relationship in a mouse model.
J Osteopath Med; 120(7): 446-455

Relationship Between Elevated Automatic Blood Pressure Readings and Manual Blood Pressure Readings in Adult Patients With Normal and High Body Mass Index

Munif M. Hussain, DO, MS; Ian E. Solomon, DO; Vanessa Pazdernik, MS; Sushant Bandarpalle, DO; Isaac Navarro, DMD, MPH; Tanya Shneyder, DO; and Lawrence LeBeau, DO
Discrepancies in ambulatory blood pressure readings exist between automated blood pressure machines and manual mercury sphygmomanometers. These differences and their relationship with body mass index were explored in this study of 281 patients.
J Osteopath Med; 119(6): 364-370

Correction to Clearfield et al 2018;118 (11):719-729. doi:10.7556/jaoa.2018.157

In the byline, the last name for coauthor Jennifer Weiss, DO, was misspelled as Weis. (doi:10.7556/jaoa.2019.049)
J Osteopath Med; 119(5): 283-283

A Pilot Study of Jugular Compression (Queckenstedt maneuver) for Cranial Movement Perception

Alessandra Abenavoli, PhD (Italy); Stefano Pisa, DO (Italy), BSc Ost (UK); and Alberto Maggiani, DO (Italy), BSc Ost (UK), PT
Eight blindfolded osteopaths evaluated the cranial movement (CM) of 6 volunteers in this study as a trained clinician applied the Q-test; results were compared to determine whether the osteopaths were able to perceive a palpable change in CM amplitude when the Q-test was applied, which the authors offer as a starting point for understanding the intracranial and extracranial mechanisms of CM.
J Osteopath Med; 120(10): 647-654

Diagnosis of Myocardial Infarction in a Patient With Left Bundle Branch Block and Negative Sgarbossa Criteria

Bryan Beaty, OMS III, and David Park, DO
The authors describe the case of an 84-year-old man with acute cardiopulmonary symptoms who was negative for modified Sgarbossa criteria but later had a confirmed diagnosis, illustrating the necessity of good clinical judgment alongside any diagnostic algorithm.
J Osteopath Med; 120(10): 655-659

Evaluation of “Spin” in the Abstracts of Randomized Controlled Trial Reports in Cardiology

William B. Roberts, MS; Craig M. Cooper, BS; Mahmood Khattab, DO; Patrick Neff, DO; Dan Wildes, DO; Cole Wayant, BS; and Matt Vassar, PhD
In an effort to assess potential influence on clinical decision making, the authors evaluated the presence of “spin” —misrepresentation or distortion of research findings that might create a false impression of validity—in the abstracts of 66 randomized controlled trials in cardiology.
J Osteopath Med; 120(11): 732-739

Straight back syndrome as a clue to diagnosing asymptomatic congenital valvular heart disease and limiting the risk of weightlifting

William A. Schiavone, DO
Although initially asymptomatic, mitral valve prolapse/myxomatous mitral valve disease (MVP/MMVD) and bicuspid aortic valve (BAV) are currently the 2 most common congenital valvular heart diseases. In this Clinical Practice overview meant to act as a primer for osteopathic physicians, the author explores possible associations between straight back syndrome (SBS) and MVP/MMVD, which may be a key to earlier diagnosis, as well as links between weightlifting and ascending aortic enlargement and with chordae tendineae rupture, where the common theme is blood pressure elevation.
J Osteopath Med; 1(2): 135-140

QTc interval prolongation associated with inpatient azithromycin therapy for pneumonia

Maricel Dela Cruz, DO, MPH; Muhammed Ershad, MD; and Ahmed Mostafa, MD
The authors retrospectively reviewed the medical records of 642 patients aged 18 years and older who were diagnosed with pneumonia and treated with azithromycin at an academic teaching hospital, to compare corrected QT (QTc) interval measurements on electrocardiogram (ECG) before and after treatment in response to a 2013 warning from the US Food and Drug Administration regarding the use of azithromycin and the risk of fatal dysrhythmias.
J Osteopath Med; 1(1): 5-9

Mobitz Type II Atrioventricular Heart Block After Candlenut Ingestion

Andrew L. Koons, DO; Lexis T. Laubach, BS; Kenneth D. Katz, MD; and Gillian A. Beauchamp, MD
The authors present the case of a 44 year old woman who developed a second degree, Mobitz type II atrioventricular block after consumption of a candlenut, a highly accessible seed marketed as a natural weight loss supplement.
J Am Osteopath Assoc; 120(12): 839-843

Readmission Risk Factors and Heart Failure With Preserved Ejection Fraction

Dustin Harmon, DO; Jennifer Rathousky, DO; Faiza Choudhry, DO; Harjot Grover, DO; Ishwar Patel, DO; Teresa Jacobson, MSA; Judith Boura, MS; Joan Crawford, DO; and Jelena Arnautovic, DO
Heart failure with preserved ejection fraction (HFpEF) is now more common than heart failure with reduced ejection fraction, affecting more than 50% of patients with the heart failure. In this study, the authors worked to identify risk factors for readmission in patients discharged with a diagnosis of HFpEF.
J Am Osteopath Assoc; 120(12): 831-838